Why Must Exosomes Be Kept in a Continuous Cold Chain?

—— Preserving the Bio-activity of "Cellular Messengers"

Exosomes are biological nanoparticles with a diameter of only 30–150 nm that mediate precise intercellular communication by encapsulating nucleic acids, proteins, and lipids. Research indicates that the bio-efficacy of exosomes is highly dependent on the structural integrity of their lipid bilayer.

However, exosomes are extremely sensitive to their environment. Unstable storage conditions, temperature fluctuations, or repeated freeze-thaw cycles can easily induce vesicle aggregation, membrane damage, and loss of function. The International Society for Extracellular Vesicles (ISEV) recommends cryopreservation at -80°C as the standard for long-term storage, while short-term use (≤72 hours) must be maintained at a constant 4°C to prevent inactivation.

At Ebovir, we understand that "Activity is Life." To ensure the cutting-edge restorative power of every drop of our exosomes, we have established a rigorous Full Cold-Chain Logistics protocol. From clinical-grade laboratory extraction and high-standard storage to the final step of delivery into your hands, Ebovir maintains a stable, closed-loop temperature control system, eliminating any loss of bio-activity caused by temperature variations.

Choosing Ebovir means choosing "Live" technology, strictly guarded by science.

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